OR4C16

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Olfactory receptor, family 4, subfamily C, member 16
Identifiers
Symbol(s) OR4C16; OR11-135
External IDs MGI3031043 HomoloGene88377
Orthologs
Human Mouse
Entrez 219428 258453
Ensembl ENSG00000181935 ENSMUSG00000075113
Uniprot Q8NGL9 n/a
Refseq NM_001004701 (mRNA)
NP_001004701 (protein)
NM_146461 (mRNA)
NP_666672 (protein)
Location Chr 11: 55.1 - 55.1 Mb Chr 2: 88.71 - 88.71 Mb
Pubmed search [1] [2]

Olfactory receptor, family 4, subfamily C, member 16, also known as OR4C16, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 
  • Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification.". Nature 440 (7083): 497–500. doi:10.1038/nature04632. PMID 16554811. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.