OR2T12

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Olfactory receptor, family 2, subfamily T, member 12
Identifiers
Symbol(s) OR2T12; OR1-57
External IDs HomoloGene88370
Orthologs
Human Mouse
Entrez 127064 n/a
Ensembl ENSG00000177201 n/a
Uniprot Q8NG77 n/a
Refseq NM_001004692 (mRNA)
NP_001004692 (protein)
n/a (mRNA)
n/a (protein)
Location Chr 1: 246.52 - 246.53 Mb n/a
Pubmed search [1] n/a

Olfactory receptor, family 2, subfamily T, member 12, also known as OR2T12, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

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[edit] Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052. 
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.