OR2M4
From Wikipedia, the free encyclopedia
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Olfactory receptor, family 2, subfamily M, member 4
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| Identifiers | ||||||||||||||
| Symbol(s) | OR2M4; HSHTPCRX18; HTPCRX18; OR1-55; OST710; TPCR100 | |||||||||||||
| External IDs | HomoloGene: 88846 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 26245 | n/a | ||||||||||||
| Ensembl | ENSG00000171180 | n/a | ||||||||||||
| Uniprot | Q96R27 | n/a | ||||||||||||
| Refseq | NM_017504 (mRNA) NP_059974 (protein) |
n/a (mRNA) n/a (protein) |
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| Location | Chr 1: 246.47 - 246.47 Mb | n/a | ||||||||||||
| Pubmed search | [1] | n/a | ||||||||||||
Olfactory receptor, family 2, subfamily M, member 4, also known as OR2M4, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells.". Nature 355 (6359): 453-5. doi:. PMID 1370859.
- Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.". Genomics 39 (3): 239-46. doi:. PMID 9119360.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:. PMID 16710414.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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