OR2M3

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Olfactory receptor, family 2, subfamily M, member 3
Identifiers
Symbol(s) OR2M3; OR1-54; OR2M3P; OR2M6; OST003
External IDs MGI3029999 HomoloGene66210
Orthologs
Human Mouse
Entrez 127062 258458
Ensembl ENSG00000177233 ENSMUSG00000050158
Uniprot Q8NG83 n/a
Refseq NM_001004689 (mRNA)
NP_001004689 (protein)
NM_146466 (mRNA)
NP_666677 (protein)
Location Chr 1: 246.43 - 246.43 Mb Chr 16: 19.32 - 19.32 Mb
Pubmed search [1] [2]

Olfactory receptor, family 2, subfamily M, member 3, also known as OR2M3, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052. 
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.