OR2L8

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Olfactory receptor, family 2, subfamily L, member 8
Identifiers
Symbol(s) OR2L8;
External IDs MGI3030002 HomoloGene84569
Orthologs
Human Mouse
Entrez 391190 258354
Ensembl ENSG00000196936 ENSMUSG00000061361
Uniprot Q8NGY9 n/a
Refseq NM_001001963 (mRNA)
NP_001001963 (protein)
NM_146357 (mRNA)
NP_666469 (protein)
Location Chr 1: 246.18 - 246.18 Mb Chr 16: 19.44 - 19.44 Mb
Pubmed search [1] [2]

Olfactory receptor, family 2, subfamily L, member 8, also known as OR2L8, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

[edit] See also

[edit] References

[edit] Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.