OR2L2

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Olfactory receptor, family 2, subfamily L, member 2
Identifiers
Symbol(s) OR2L2; HSHTPCRH07; HTPCRH07; OR1-48; OR2L12; OR2L4P
External IDs HomoloGene78689
Orthologs
Human Mouse
Entrez 26246 n/a
Ensembl ENSG00000203663 n/a
Uniprot Q8NH16 n/a
Refseq NM_001004686 (mRNA)
NP_001004686 (protein)
n/a (mRNA)
n/a (protein)
Location Chr 1: 246.27 - 246.27 Mb n/a
Pubmed search [1] n/a

Olfactory receptor, family 2, subfamily L, member 2, also known as OR2L2, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] Further reading

  • Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells.". Nature 355 (6359): 453-5. doi:10.1038/355453a0. PMID 1370859. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.