OR2AG1
From Wikipedia, the free encyclopedia
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Olfactory receptor, family 2, subfamily AG, member 1
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| Identifiers | ||||||||||||||
| Symbol(s) | OR2AG1; OR11-79; OR2AG3 | |||||||||||||
| External IDs | MGI: 3030539 HomoloGene: 12558 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 144125 | 259034 | ||||||||||||
| Ensembl | ENSG00000170803 | ENSMUSG00000047120 | ||||||||||||
| Uniprot | Q9H205 | n/a | ||||||||||||
| Refseq | NM_001004489 (mRNA) NP_001004489 (protein) |
NM_147032 (mRNA) NP_667243 (protein) |
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| Location | Chr 11: 6.76 - 6.76 Mb | Chr 7: 106.67 - 106.67 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Olfactory receptor, family 2, subfamily AG, member 1, also known as OR2AG1, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Lane RP, Cutforth T, Young J, et al. (2001). "Genomic analysis of orthologous mouse and human olfactory receptor loci.". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7390–5. doi:. PMID 11416212.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. PMID 12213199.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052.
- Neuhaus EM, Mashukova A, Zhang W, et al. (2006). "A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins.". Chem. Senses 31 (5): 445–52. doi:. PMID 16565291.
- Mashukova A, Spehr M, Hatt H, Neuhaus EM (2006). "Beta-arrestin2-mediated internalization of mammalian odorant receptors.". J. Neurosci. 26 (39): 9902–12. doi:. PMID 17005854.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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