OR2AE1
From Wikipedia, the free encyclopedia
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Olfactory receptor, family 2, subfamily AE, member 1
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| Identifiers | ||||||||||||||
| Symbol(s) | OR2AE1; OR2AE2 | |||||||||||||
| External IDs | MGI: 3030004 HomoloGene: 79678 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 81392 | 258959 | ||||||||||||
| Ensembl | ENSG00000176607 | ENSMUSG00000062245 | ||||||||||||
| Uniprot | Q8NHA4 | n/a | ||||||||||||
| Refseq | NM_001005276 (mRNA) NP_001005276 (protein) |
NM_146957 (mRNA) NP_667168 (protein) |
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| Location | Chr 7: 99.31 - 99.31 Mb | Chr 16: 19.52 - 19.52 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Olfactory receptor, family 2, subfamily AE, member 1, also known as OR2AE1, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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[edit] See also
[edit] References
[edit] Further reading
- "Toward a complete human genome sequence." (1999). Genome Res. 8 (11): 1097–108. PMID 9847074.
- Thompson EE, Kuttab-Boulos H, Yang L, et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster.". Pharmacogenomics J. 6 (2): 105–14. doi:. PMID 16314882.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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