OR1S1

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Olfactory receptor, family 1, subfamily S, member 1
Identifiers
Symbol(s) OR1S1; OR11-232; OST034
External IDs MGI3031330 HomoloGene17458
Orthologs
Human Mouse
Entrez 219959 258991
Ensembl ENSG00000172774 ENSMUSG00000048356
Uniprot Q8NH92 n/a
Refseq NM_001004458 (mRNA)
NP_001004458 (protein)
NM_146989 (mRNA)
NP_667200 (protein)
Location Chr 11: 57.74 - 57.74 Mb Chr 19: 13.85 - 13.85 Mb
Pubmed search [1] [2]

Olfactory receptor, family 1, subfamily S, member 1, also known as OR1S1, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

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[edit] Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.