OR1J2
From Wikipedia, the free encyclopedia
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Olfactory receptor, family 1, subfamily J, member 2
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| Identifiers | ||||||||||||||
| Symbol(s) | OR1J2; FLJ16828; HG152; HSA5; OR1J3; OR1J5; OR9-19; OST044 | |||||||||||||
| External IDs | MGI: 3030186 HomoloGene: 73996 | |||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 26740 | 258942 | ||||||||||||
| Ensembl | n/a | ENSMUSG00000053146 | ||||||||||||
| Refseq | NM_054107 (mRNA) NP_473448 (protein) |
NM_146940 (mRNA) NP_667151 (protein) |
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| Location | n/a | Chr 2: 36.69 - 36.69 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Olfactory receptor, family 1, subfamily J, member 2, also known as OR1J2, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells.". Nature 355 (6359): 453–5. doi:. PMID 1370859.
- Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:. PMID 10706615.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. PMID 12213199.
- Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees.". Am. J. Hum. Genet. 73 (3): 489–501. doi:. PMID 12908129.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:. PMID 14702039.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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