From Wikipedia, the free encyclopedia
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Olfactory receptor, family 1, subfamily F, member 2
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| Identifiers |
| Symbol(s) |
OR1F2; OLFMF2; OR16-3; OR1F11; OR1F2P; OR1F3P; hg91 |
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| Orthologs |
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Human |
Mouse |
| Entrez |
26184 |
n/a
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| Pubmed search |
[1] |
n/a |
Olfactory receptor, family 1, subfamily F, member 2, also known as OR1F2, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
[edit] See also
[edit] References
[edit] Further reading
- Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells.". Nature 355 (6359): 453-5. doi:10.1038/355453a0. PMID 1370859.
- Bernot A, Heilig R, Clepet C, et al. (1998). "A transcriptional Map of the FMF region.". Genomics 50 (2): 147-60. PMID 9653642.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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G protein-coupled receptors: olfactory receptors |
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Class I
(fish-like specific receptors) |
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Family 51
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Family 52
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Family 56
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Class II
(tetrapod specific receptors) |
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Family 1
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Family 2
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Family 10
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Family 11
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Family 12
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Family 13
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