OR13H1
From Wikipedia, the free encyclopedia
|
Olfactory receptor, family 13, subfamily H, member 1
|
||||||||||||||
| Identifiers | ||||||||||||||
| Symbol(s) | OR13H1; ORX1 | |||||||||||||
| External IDs | MGI: 1333887 HomoloGene: 27122 | |||||||||||||
|
||||||||||||||
| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 347468 | 18363 | ||||||||||||
| Ensembl | ENSG00000171054 | ENSMUSG00000043698 | ||||||||||||
| Uniprot | Q8NG92 | n/a | ||||||||||||
| Refseq | NM_001004486 (mRNA) NP_001004486 (protein) |
NM_146315 (mRNA) NP_666427 (protein) |
||||||||||||
| Location | Chr X: 130.51 - 130.51 Mb | Chr 4: 118.15 - 118.16 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Olfactory receptor, family 13, subfamily H, member 1, also known as OR13H1, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
Contents |
[edit] See also
[edit] References
[edit] Further reading
- Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells.". Nature 355 (6359): 453–5. doi:. PMID 1370859.
- Buck L, Axel R (1991). "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition.". Cell 65 (1): 175–87. PMID 1840504.
- Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome.". Biochem. Biophys. Res. Commun. 237 (2): 283–7. doi:. PMID 9268701.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. PMID 12213199.
- Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees.". Am. J. Hum. Genet. 73 (3): 489–501. doi:. PMID 12908129.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052.
- Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325–37. doi:. PMID 15772651.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
 |
This membrane protein-related article is a stub. You can help Wikipedia by expanding it. |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||
