OR13C4

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Olfactory receptor, family 13, subfamily C, member 4
Identifiers
Symbol(s) OR13C4; HSHTPCRX17; HTPCRX17; OR2K1; OR37F; OR9-7
External IDs MGI3030107 HomoloGene85937
Orthologs
Human Mouse
Entrez 138804 258821
Ensembl ENSG00000148136 ENSMUSG00000049648
Uniprot Q8NGS5 n/a
Refseq NM_001001919 (mRNA)
NP_001001919 (protein)
NM_146824 (mRNA)
NP_667035 (protein)
Location Chr 9: 106.33 - 106.33 Mb Chr 4: 52.88 - 52.88 Mb
Pubmed search [1] [2]

Olfactory receptor, family 13, subfamily C, member 4, also known as OR13C4, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] Further reading

  • Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells.". Nature 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859. 
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. PMID 12213199. 
  • Hoppe R, Breer H, Strotmann J (2004). "Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.". Genomics 82 (3): 355–64. PMID 12906860. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 
  • Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMID 15164053. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.