OR11A1

From Wikipedia, the free encyclopedia


Olfactory receptor, family 11, subfamily A, member 1
Identifiers
Symbol(s) OR11A1; OR11A2; dJ994E9.6; hs6M1-18
External IDs MGI2177479 HomoloGene27189
Orthologs
Human Mouse
Entrez 26531 258507
Ensembl n/a ENSMUSG00000064121
Refseq NM_013937 (mRNA)
NP_039225 (protein)
NM_146514 (mRNA)
NP_666725 (protein)
Location n/a Chr 17: 36.83 - 36.83 Mb
Pubmed search [1] [2]

Olfactory receptor, family 11, subfamily A, member 1, also known as OR11A1, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

[edit] See also

[edit] References

[edit] Further reading

  • Volz A, Ehlers A, Younger R, et al. (2003). "Complex transcription and splicing of odorant receptor genes.". J. Biol. Chem. 278 (22): 19691-701. doi:10.1074/jbc.M212424200. PMID 12637542. 
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.