OR10J5

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Olfactory receptor, family 10, subfamily J, member 5
Identifiers
Symbol(s) OR10J5; OR1-28
External IDs MGI106648 HomoloGene7460
Orthologs
Human Mouse
Entrez 127385 18313
Ensembl ENSG00000184155 ENSMUSG00000037924
Uniprot Q8NHC4 n/a
Refseq NM_001004469 (mRNA)
NP_001004469 (protein)
NM_008763 (mRNA)
NP_032789 (protein)
Location Chr 1: 157.77 - 157.77 Mb Chr 1: 174.79 - 174.79 Mb
Pubmed search [1] [2]

Olfactory receptor, family 10, subfamily J, member 5, also known as OR10J5, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] Further reading

  • Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees.". Am. J. Hum. Genet. 73 (3): 489-501. doi:10.1086/378132. PMID 12908129. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.