Ohio and Mississippi Railroad
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The Mississippi and Ohio Railroad was a railroad operating between Cincinnati, Ohio and East St. Louis, Illinois from 1857 to 1893.
The railroad started in 1854 and paralleled the Cincinnati and Whitewater Canal. Its East St. Louis terminal near the Mississippi River was completed in 1857. It was a founding rail line of the Terminal Railroad Association of St. Louis
On September 17, 1861, during the American Civil War a train carrying union troops fell through a sabotaged bridge at Huron, Indiana injuring or killing 100.
On October 6th, 1866 the Adams Express Company car was robbed by the Reno Gang just east of Seymour, Indiana becoming the first train robbery in US history.
It merged in 1893 with the Baltimore and Ohio Railroad (which in turn became part of the CSX railroad).