Office of National Emergency

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Office of National Emergency
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Publication information
Publisher	Marvel Comics
First appearance	Decimation: House of M - The Day After one-shot
Created by	Chris Claremont Randy Green Aaron Lopresti
In story information
Type of organization	Government agency
Base(s)	O*N*E Headquarters
Leader(s)	General Demetrius Lazer (Director of O*N*E) Valerie Cooper (Deputy Director of O*N*E) James Rhodes (Direct Command Officer / Instructor)
Agent(s)	Bishop Colonel Miguel Reyes Jeremiah Muldoon/Meld Alexander Lexington/Lex Emil Winston Nathaniel Briggs Jake Slayton Randall Nixon/Stilts Rajani Dhama/Joni Tracy Skylark/Sky Jennings

The Office of National Emergency, most commonly referred to as O*N*E*, is a fictional government agency in the Marvel Universe. It is best known as the originator of the Sentinel squads that were assigned to protect/observe the X-Men and the remaining mutants after the event known as M-Day, which reduced the number of mutants on Earth to a very few hundred.

The Sentinels employed by O*N*E are Mark VIII models which, unlike most, require pilots.

A limited series by John Layman named Sentinel Squad O*N*E spotlighted the original squad.