O-pyrocatechuate decarboxylase

From Wikipedia, the free encyclopedia

In enzymology, an o-pyrocatechuate decarboxylase (EC 4.1.1.46) is an enzyme that catalyzes the chemical reaction

2,3-dihydroxybenzoate catechol + CO₂

Hence, this enzyme has one substrate, 2,3-dihydroxybenzoate, and two products, catechol and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2,3-dihydroxybenzoate carboxy-lyase (catechol-forming). This enzyme is also called 2,3-dihydroxybenzoate carboxy-lyase. This enzyme participates in benzoate degradation via hydroxylation and carbazole degradation.

[edit] References

• IUBMB entry for 4.1.1.46
• BRENDA references for 4.1.1.46 (Recommended.)
• PubMed references for 4.1.1.46
• PubMed Central references for 4.1.1.46
• Google Scholar references for 4.1.1.46
• Rao PV, Moore K, Towers GH (1967). "O-pyrocatechiuc acid carboxy-lyase from Aspergillus niger". Arch. Biochem. Biophys. 122: 466–73. doi:10.1016/0003-9861(67)90220-2. PMID 6066253. 

[edit] External links

The CAS registry number for this enzyme class is 37289-48-8.

• IUBMB entry for 4.1.1.46

• KEGG entry for 4.1.1.46

• BRENDA entry for 4.1.1.46

• NiceZyme view of 4.1.1.46

• EC2PDB: PDB structures for 4.1.1.46

• PRIAM entry for 4.1.1.46

• PUMA2 entry for 4.1.1.46

• IntEnz: Integrated Enzyme entry for 4.1.1.46

• MetaCyc entry for 4.1.1.46

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050150: o-pyrocatechuate decarboxylase

• AMIGO entry for GO code 0050150: o-pyrocatechuate decarboxylase