O-phosphoserine sulfhydrylase
From Wikipedia, the free encyclopedia
In enzymology, an O-phosphoserine sulfhydrylase (EC 2.5.1.65) is an enzyme that catalyzes the chemical reaction
- O-phospho-L-serine + hydrogen sulfide
L-cysteine + phosphate
Thus, the two substrates of this enzyme are O-phospho-L-serine and hydrogen sulfide, whereas its two products are L-cysteine and phosphate.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase. This enzyme is also called O-phosphoserine(thiol)-lyase. This enzyme participates in cysteine metabolism and sulfur metabolism.
[edit] References
- IUBMB entry for 2.5.1.65
- BRENDA references for 2.5.1.65 (Recommended.)
- PubMed references for 2.5.1.65
- PubMed Central references for 2.5.1.65
- Google Scholar references for 2.5.1.65
- Mino K, Ishikawa K (2003). "A novel O-phospho-L-serine sulfhydrylation reaction catalyzed by O-acetylserine sulfhydrylase from Aeropyrum pernix K1". FEBS. Lett. 551: 133–8. doi:. PMID 12965218.
- Mino K, Ishikawa K (2003). "Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1". J. Bacteriol. 185: 2277–84. doi:. PMID 12644499.
- Mino K, Oda Y, Ataka M, Ishikawa K (2003). "Crystallization and preliminary X-ray diffraction analysis of O-acetylserine sulfhydrylase from Aeropyrum pernix K1". Acta. Crystallogr. D. Biol. Crystallogr. 59: 338–40. doi:. PMID 12554945.
[edit] External links
 |
This transferase article is a stub. You can help Wikipedia by expanding it. |
