NUPR1

From Wikipedia, the free encyclopedia


Nuclear protein 1
Identifiers
Symbol(s) NUPR1; P8; COM1
External IDs MGI: 1891834 HomoloGene: 8229
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 26471 56312
Ensembl ENSG00000176046 ENSMUSG00000030717
Uniprot O60356 Q9D756
Refseq NM_001042483 (mRNA)
NP_001035948 (protein)		 NM_019738 (mRNA)
NP_062712 (protein)
Location Chr 16: 28.46 - 28.46 Mb Chr 7: 126.41 - 126.42 Mb
Pubmed search [1] [2]

Nuclear protein 1, also known as NUPR1, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: NUPR1 nuclear protein 1.

[edit] Further reading

  • Mallo GV, Fiedler F, Calvo EL, et al. (1998). "Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth.". J. Biol. Chem. 272 (51): 32360–9. PMID 9405444. 
  • Vasseur S, Vidal Mallo G, Fiedler F, et al. (1999). "Cloning and expression of the human p8, a nuclear protein with mitogenic activity.". Eur. J. Biochem. 259 (3): 670–5. PMID 10092851. 
  • Ree AH, Tvermyr M, Engebraaten O, et al. (1999). "Expression of a novel factor in human breast cancer cells with metastatic potential.". Cancer Res. 59 (18): 4675–80. PMID 10493524. 
  • Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.". Genomics 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829. 
  • Hoffmeister A, Ropolo A, Vasseur S, et al. (2002). "The HMG-I/Y-related protein p8 binds to p300 and Pax2 trans-activation domain-interacting protein to regulate the trans-activation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter.". J. Biol. Chem. 277 (25): 22314–9. doi:10.1074/jbc.M201657200. PMID 11940591. 
  • Ree AH, Bratland A, Kroes RA, et al. (2002). "Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases.". Anticancer Res. 22 (4): 1949–57. PMID 12174869. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Jiang WG, Davies G, Fodstad O (2005). "Com-1/P8 in oestrogen regulated growth of breast cancer cells, the ER-beta connection.". Biochem. Biophys. Res. Commun. 330 (1): 253–62. doi:10.1016/j.bbrc.2005.02.157. PMID 15781258. 
  • Mao Y, Zhao Y, Zhou LF, et al. (2006). "A novel gene mutation (1292 deletion) in a Chinese family with cerebral cavernous malformations.". Neurosurgery 56 (5): 1149–53; discussion 1149–53. PMID 15854263. 
  • Ito Y, Yoshida H, Motoo Y, et al. (2005). "Expression of p8 protein in medullary thyroid carcinoma.". Anticancer Res. 25 (5): 3419–23. PMID 16101158. 
  • Valacco MP, Varone C, Malicet C, et al. (2006). "Cell growth-dependent subcellular localization of p8.". J. Cell. Biochem. 97 (5): 1066–79. doi:10.1002/jcb.20682. PMID 16294328. 
  • Malicet C, Hoffmeister A, Moreno S, et al. (2006). "Interaction of the stress protein p8 with Jab1 is required for Jab1-dependent p27 nuclear-to-cytoplasm translocation.". Biochem. Biophys. Res. Commun. 339 (1): 284–9. doi:10.1016/j.bbrc.2005.11.018. PMID 16300740. 
  • Malicet C, Giroux V, Vasseur S, et al. (2006). "Regulation of apoptosis by the p8/prothymosin alpha complex.". Proc. Natl. Acad. Sci. U.S.A. 103 (8): 2671–6. doi:10.1073/pnas.0508955103. PMID 16478804. 
  • Malicet C, Dagorn JC, Neira JL, Iovanna JL (2006). "p8 and prothymosin alpha: unity is strength.". Cell Cycle 5 (8): 829–30. PMID 16628001. 
  • Jiang WG, Davies G, Martin TA, et al. (2007). "Com-1/p8 acts as a putative tumour suppressor in prostate cancer.". Int. J. Mol. Med. 18 (5): 981–6. PMID 17016631. 
  • Ishida M, Miyamoto M, Naitoh S, et al. (2007). "The SYT-SSX fusion protein down-regulates the cell proliferation regulator COM1 in t(x;18) synovial sarcoma.". Mol. Cell. Biol. 27 (4): 1348–55. doi:10.1128/MCB.00658-06. PMID 17101797. 
  • Goruppi S, Patten RD, Force T, Kyriakis JM (2007). "Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction.". Mol. Cell. Biol. 27 (3): 993–1006. doi:10.1128/MCB.00996-06. PMID 17116693. 
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