NUP43

From Wikipedia, the free encyclopedia


Nucleoporin 43kDa
Identifiers
Symbol(s) NUP43; p42; FLJ13287; bA350J20.1
External IDs OMIM: 608141 MGI1917162 HomoloGene11639
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 348995 69912
Ensembl ENSG00000120253 ENSMUSG00000040034
Uniprot Q8NFH3 Q3UJY4
Refseq NM_198887 (mRNA)
NP_942590 (protein)
NM_145706 (mRNA)
NP_663752 (protein)
Location Chr 6: 150.09 - 150.11 Mb Chr 10: 7.36 - 7.37 Mb
Pubmed search [1] [2]

Nucleoporin 43kDa, also known as NUP43, is a human gene.[1]

Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004).[supplied by OMIM][1]

[edit] References

[edit] Further reading

  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166. 
  • Cronshaw JM, Krutchinsky AN, Zhang W, et al. (2002). "Proteomic analysis of the mammalian nuclear pore complex.". J. Cell Biol. 158 (5): 915–27. doi:10.1083/jcb.200206106. PMID 12196509. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Loïodice I, Alves A, Rabut G, et al. (2005). "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.". Mol. Biol. Cell 15 (7): 3333–44. doi:10.1091/mbc.E03-12-0878. PMID 15146057. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336. 
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.