NUP155

From Wikipedia, the free encyclopedia

Nucleoporin 155kDa

Identifiers

NUP155; KIAA0791; N155

External IDs

OMIM: 606694 MGI: 2181182 HomoloGene: 43155

Gene ontology
Molecular Function:	• transporter activity • nucleocytoplasmic transporter activity • structural constituent of nuclear pore
Cellular Component:	• nucleus • nuclear pore
Biological Process:	• transport • nucleocytoplasmic transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_004298 (mRNA)
NP_004289 (protein)

NM_133227 (mRNA)
NP_573490 (protein)

Location

Chr 5: 37.32 - 37.41 Mb

Chr 15: 8.06 - 8.11 Mb

Pubmed search

[1]

[2]

Nucleoporin 155kDa, also known as NUP155, is a human gene.^[1]

Nucleoporins are the main components of the nuclear pore complex (NPC) of eukaryotic cells. They are involved in the bidirectional trafficking of molecules, especially mRNAs and proteins, between the nucleus and the cytoplasm. The protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. Two protein isoforms are encoded by transcript variants of this gene.^[1]

[edit] References

^ ^a ^b Entrez Gene: NUP155 nucleoporin 155kDa.

[edit] Further reading

Görlich D, Mattaj IW (1996). "Nucleocytoplasmic transport.". Science 271 (5255): 1513–8. PMID 8599106.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (5): 277–86. PMID 9872452.
Zhang X, Yang H, Corydon MJ, et al. (1999). "Localization of a human nucleoporin 155 gene (NUP155) to the 5p13 region and cloning of its cDNA.". Genomics 57 (1): 144–51. doi:10.1006/geno.1999.5741. PMID 10191094.
Zhang X, Yang H, Yu J, et al. (2002). "Genomic organization, transcript variants and comparative analysis of the human nucleoporin 155 (NUP155) gene.". Gene 288 (1-2): 9–18. PMID 12034489.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Rayala HJ, Kendirgi F, Barry DM, et al. (2004). "The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155.". Mol. Cell Proteomics 3 (2): 145–55. doi:10.1074/mcp.M300106-MCP200. PMID 14645504.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Hawryluk-Gara LA, Shibuya EK, Wozniak RW (2005). "Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex.". Mol. Biol. Cell 16 (5): 2382–94. doi:10.1091/mbc.E04-10-0857. PMID 15703211.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.