NUMBL

From Wikipedia, the free encyclopedia


Numb homolog (Drosophila)-like
Identifiers
Symbol(s) NUMBL; CAG3A; CTG3a; NBL; NUMB-R; NUMBR; TNRC23
External IDs OMIM: 604018 MGI: 894702 HomoloGene: 68413
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 9253 18223
Ensembl ENSG00000105245 ENSMUSG00000063160
Uniprot Q9Y6R0 Q3UH86
Refseq NM_004756 (mRNA)
NP_004747 (protein)		 NM_010950 (mRNA)
NP_035080 (protein)
Location Chr 19: 45.86 - 45.89 Mb Chr 7: 26.97 - 26.99 Mb
Pubmed search [1] [2]

Numb homolog (Drosophila)-like, also known as NUMBL, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: NUMBL numb homolog (Drosophila)-like.

[edit] Further reading

  • Wong WT, Schumacher C, Salcini AE, et al. (1995). "A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution.". Proc. Natl. Acad. Sci. U.S.A. 92 (21): 9530-4. PMID 7568168. 
  • Zhong W, Feder JN, Jiang MM, et al. (1996). "Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis.". Neuron 17 (1): 43-53. PMID 8755477. 
  • Zhong W, Jiang MM, Weinmaster G, et al. (1997). "Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis.". Development 124 (10): 1887-97. PMID 9169836. 
  • Margolis RL, Abraham MR, Gatchell SB, et al. (1997). "cDNAs with long CAG trinucleotide repeats from human brain.". Hum. Genet. 100 (1): 114-22. PMID 9225980. 
  • Salcini AE, Confalonieri S, Doria M, et al. (1997). "Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.". Genes Dev. 11 (17): 2239-49. PMID 9303539. 
  • Roncarati R, Sestan N, Scheinfeld MH, et al. (2002). "The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling.". Proc. Natl. Acad. Sci. U.S.A. 99 (10): 7102-7. doi:10.1073/pnas.102192599. PMID 12011466. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801-14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
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