NUFIP1

From Wikipedia, the free encyclopedia

Nuclear fragile X mental retardation protein interacting protein 1

Identifiers

External IDs

OMIM: 604354 MGI: 1351474 HomoloGene: 8216

Gene ontology
Molecular Function:	• DNA binding • RNA binding • protein binding • zinc ion binding • metal ion binding
Cellular Component:	• intracellular • nucleus • perichromatin fibrils • nucleolus • cytosolic ribosome (sensu Eukaryota) • transcription elongation factor complex • nuclear matrix • presynaptic active zone
Biological Process:	• RNA processing • positive regulation of transcription from RNA polymerase II promoter

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_012345 (mRNA)
NP_036477 (protein)

NM_013745 (mRNA)
NP_038773 (protein)

Location

Chr 13: 44.41 - 44.46 Mb

Chr 14: 74.85 - 74.87 Mb

Pubmed search

[1]

[2]

Nuclear fragile X mental retardation protein interacting protein 1, also known as NUFIP1, is a human gene.^[1]

[edit] References

^ Entrez Gene: NUFIP1 nuclear fragile X mental retardation protein interacting protein 1.

[edit] Further reading

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Cabart P, Chew HK, Murphy S (2004). "BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II.". Oncogene 23 (31): 5316-29. doi:10.1038/sj.onc.1207684. PMID 15107825.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522-8. doi:10.1038/nature02379. PMID 15057823.
Bardoni B, Willemsen R, Weiler IJ, et al. (2003). "NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosomes.". Exp. Cell Res. 289 (1): 95-107. PMID 12941608.
Bardoni B, Castets M, Huot ME, et al. (2003). "82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization.". Hum. Mol. Genet. 12 (14): 1689-98. PMID 12837692.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Bardoni B, Giglio S, Schenck A, et al. (2000). "Assignment of NUFIP1 (nuclear FMRP interacting protein 1) gene to chromosome 13q14 and assignment of a pseudogene to chromosome 6q12.". Cytogenet. Cell Genet. 89 (1-2): 11-3. PMID 10894927.
Bardoni B, Schenck A, Mandel JL (2000). "A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein.". Hum. Mol. Genet. 8 (13): 2557-66. PMID 10556305.