NUDC

From Wikipedia, the free encyclopedia

Nuclear distribution gene C homolog (A. nidulans)

PDB rendering based on 2cr0.

Available structures: 2cr0

Identifiers

Symbol(s)

NUDC; HNUDC; MNUDC; NPD011

External IDs

OMIM: 610325 MGI: 106014 HomoloGene: 4812

Gene ontology
Cellular Component:	• nucleus • cytoplasm • cytoskeleton • microtubule
Biological Process:	• regulation of progression through cell cycle • cell cycle • mitosis • multicellular organismal development • cell proliferation • cell division

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006600 (mRNA)
NP_006591 (protein)

NM_010948 (mRNA)
NP_035078 (protein)

Location

Chr 1: 27.12 - 27.15 Mb

Chr 4: 132.8 - 132.82 Mb

Pubmed search

[1]

[2]

Nuclear distribution gene C homolog (A. nidulans), also known as NUDC, is a human gene.^[1]

[edit] References

^ Entrez Gene: NUDC nuclear distribution gene C homolog (A. nidulans).

[edit] Further reading

Morris SM, Albrecht U, Reiner O, et al. (1998). "The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC.". Curr. Biol. 8 (10): 603–6. PMID 9601647.
Miller BA, Zhang MY, Gocke CD, et al. (1999). "A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis.". Exp. Hematol. 27 (4): 742–50. PMID 10210332.
Matsumoto N, Ledbetter DH (1999). "Molecular cloning and characterization of the human NUDC gene.". Hum. Genet. 104 (6): 498–504. PMID 10453739.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Aumais JP, Tunstead JR, McNeil RS, et al. (2002). "NudC associates with Lis1 and the dynein motor at the leading pole of neurons.". J. Neurosci. 21 (24): RC187. PMID 11734602.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Aumais JP, Williams SN, Luo W, et al. (2004). "Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis.". J. Cell. Sci. 116 (Pt 10): 1991–2003. doi:10.1242/jcs.00412. PMID 12679384.
Zhou T, Aumais JP, Liu X, et al. (2003). "A role for Plk1 phosphorylation of NudC in cytokinesis.". Dev. Cell 5 (1): 127–38. PMID 12852857.
Lin SH, Nishino M, Luo W, et al. (2004). "Inhibition of prostate tumor growth by overexpression of NudC, a microtubule motor-associated protein.". Oncogene 23 (14): 2499–506. doi:10.1038/sj.onc.1207343. PMID 14676831.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.
Pan RM, Yang Y, Wei MX, et al. (2006). "A microtubule associated protein (hNUDC) binds to the extracellular domain of thrombopoietin receptor (Mpl).". J. Cell. Biochem. 96 (4): 741–50. doi:10.1002/jcb.20573. PMID 16088917.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Nishino M, Kurasawa Y, Evans R, et al. (2006). "NudC is required for Plk1 targeting to the kinetochore and chromosome congression.". Curr. Biol. 16 (14): 1414–21. doi:10.1016/j.cub.2006.05.052. PMID 16860740.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.