Talk:Nucleotide

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I uploaded two images in the "Synthesis" section and i made them as thumbs as i thought that having them in full size would take too much space. Well if anyone feels that they have to be full size then go ahead and do it. BorisTM 12:20, 4 November 2005 (UTC)

Contents

[edit] Introduction

There was some redundancy like - heterocyclic nucleobase (nucleobases by definition are heterocyclic), pentose sugar (pentose by definition is a sugar). Nucleotides are class of molecules and not all of them have purine or pyrimidine derivative as their base or pentose as their sugar. Boris 03:45, 16 December 2005 (UTC)

[edit] Genetic nucleotides information needed

There should be some distinction between nucleotides in nucleic acids (DNA, meaning Deoxyribonucleic acid and RNA,meaning Ribonucleic acid) and those used in other ways, most prominently ATP. Maybe there should be a few separate articles discussing these different types rather than making people have to read the articles on adenine, guanine, thymine, cytosine, and uracil and have to find the similarities for themselves.

[edit] Typo in picture

There's a typo in the first picture, but I'm not able to edit it easily.

Change 'Deoxyribose' to 'Deoxyribose'

Thanks. --64.251.84.43 03:14, 24 February 2006 (UTC)


There is another typo where is says triphoshpate


There is another typo in the first figure: "Pyramidine" should be "Pyrimidine". I cannot edit it easily. Rbcody (talk) 21:27, 17 November 2007 (UTC)

[edit] Nucleoside vs Nucleotide

I am not a biochemist by training, but all my references list the various Nucleotides as Nucleoside monophosphate, Nucleoside diphosphate, and Nucleoside triphosphate. Which is correct, or are they both correct? Ted 15:26, 28 February 2006 (UTC)

They are both correct. -- Boris 23:20, 6 March 2006 (UTC)
No. nucleoside monophosphate, or nuclelotide. saying "nucleotide monophosphate" is redundant, as "nucleotide" = "nucleoside phosphate" and "nucleoside phosphate monophosphate" sounds a little silly.

As far as my understanding, if a phosphate group attached it is a necleotide otherwies it is a necleoside.


Yes, I agree. There's no such things as nucleotide phosphates. It's either nucleoside phosphates, or nucleotides. 130.243.248.239 14:35, 19 November 2006 (UTC)


Yes, I also agree.

[edit] Re-write

The page was kinda confusing, and had lots of pictures but little text. I tried to improve things, but biochem isn't my strong suit and I may have just messed things up. Further, the section bases at the bottom is very messed up because of the mixture of diagrams. The pyrimidine section could definitely use a lot more text, right now it's just a single sentence that says 'look at the diagram'. WLU (talk) 14:59, 4 January 2008 (UTC)


I don't know if this is related to you or not - I found the following rather confusing:

"Nucleotide synthesis and structure A nucleotide is composed of a ring of nitrogen, carbon and oxygen atoms, a one carbon sugar (together referred to as a nucleoside) and one phosphate group."


Where it says one carbon sugar, it links to 5 carbon sugars. I believe it should say five carbon sugar. Have I misunderstood or is there an error? —Preceding unsigned comment added by 131.111.213.45 (talk) 21:34, 1 June 2008 (UTC)

You're right, should have been five carbon. Fixed now, thanks! Schu1321 (talk) 21:54, 1 June 2008 (UTC)

[edit] Un-merge kilobase

When a user looks up kilobase, he wants to find its definition quickly. Currently, kilobase just redirects to the TOP of the base pair article, which much less useful and requires manually searching through that article to find the definition of kilobase.76.85.197.151 (talk) 08:57, 11 May 2008 (UTC)

[edit] Nucleotide structural diagrams

Does anybody else feel that this schematic is an eyesore and vastly obtrusive? Surely we don't need the chemical structure of each with tri di and mono phosphates. Wisdom89 (T / C) 03:23, 20 May 2008 (UTC)

I would agree that they seem to be a bit much for a general article. Is there somewhere else more appropriate for them? Schu1321 (talk) 03:31, 20 May 2008 (UTC)
Well, if they were removed from the article they wouldn't be orphaned. I say that each one could stay within its own article. Wisdom89 (T / C) 03:39, 20 May 2008 (UTC)
Ok, I've gone ahead and removed them. I think the article will breathe easier now. If anyone has an earnest objection to this, feel free to discuss it here. Wisdom89 (T / C) 04:21, 20 May 2008 (UTC)