Nucleoside phosphotransferase

From Wikipedia, the free encyclopedia

In enzymology, a nucleoside phosphotransferase (EC 2.7.1.77) is an enzyme that catalyzes the chemical reaction

a nucleotide + a 2'-deoxynucleoside a nucleoside + a 2'-deoxynucleoside 5'-phosphate

Thus, the two substrates of this enzyme are nucleotide and 2'-deoxynucleoside, whereas its two products are nucleoside and 2'-deoxynucleoside 5'-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is nucleotide:nucleoside 5'-phosphotransferase. Other names in common use include nonspecific nucleoside phosphotransferase, and nucleotide:3'-deoxynucleoside 5'-phosphotransferase.

[edit] References

• IUBMB entry for 2.7.1.77
• BRENDA references for 2.7.1.77 (Recommended.)
• PubMed references for 2.7.1.77
• PubMed Central references for 2.7.1.77
• Google Scholar references for 2.7.1.77
• Brunngraber EF, Chargaff E (1967). "Purification and properties of a nucleoside phosphotransferase from carrot". J. Biol. Chem. 242: 4834–40. PMID 6061424. 
• Prasher DC, Carr MC, Ives DH, Tsai TC, Frey PA (1982). "Nucleoside phosphotransferase from barley. Characterization and evidence for ping pong kinetics involving phosphoryl enzyme". J. Biol. Chem. 257: 4931–9. PMID 6279651. 

[edit] External links

The CAS registry number for this enzyme class is 9055-37-2.

• IUBMB entry for 2.7.1.77

• KEGG entry for 2.7.1.77

• BRENDA entry for 2.7.1.77

• NiceZyme view of 2.7.1.77

• EC2PDB: PDB structures for 2.7.1.77

• PRIAM entry for 2.7.1.77

• PUMA2 entry for 2.7.1.77

• IntEnz: Integrated Enzyme entry for 2.7.1.77

• MetaCyc entry for 2.7.1.77

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050146: nucleoside phosphotransferase

• AMIGO entry for GO code 0050146: nucleoside phosphotransferase