Nucleoplasmin ATPase

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In enzymology, a nucleoplasmin ATPase (EC 3.6.4.11) is an enzyme that catalyzes the chemical reaction

ATP + H₂O $\rightleftharpoons$ ADP + phosphate

Thus, the two substrates of this enzyme are ATP and H₂O, whereas its two products are ADP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to facilitate cellular and subcellular movement. The systematic name of this enzyme class is ATP phosphohydrolase (nucleosome-assembling).

[edit] References

IUBMB entry for 3.6.4.11
BRENDA references for 3.6.4.11 (Recommended.)
PubMed references for 3.6.4.11
PubMed Central references for 3.6.4.11
Google Scholar references for 3.6.4.11
Laskey RA, Mills AD, Philpott A, Leno GH, Dilworth SM, Dingwall C (1993). "The role of nucleoplasmin in chromatin assembly and disassembly". Philos. Trans. R. Soc. Lond. B. Biol. Sci. 339: 268–9. PMID 8098530.
Cote J, Quinn J, Workman JL, Peterson CL (1994). "Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex". Science. 265: 53–60. doi:10.1126/science.8016655. PMID 8016655.
Ito T, Tyler JK, Bulger M, Kobayashi R, Kadonaga JT (1996). "ATP-facilitated chromatin assembly with a nucleoplasmin-like protein from Drosophila melanogaster". J. Biol. Chem. 271: 25041–8. doi:10.1074/jbc.271.40.25041. PMID 8798787.