Nucleocytoplasmic large DNA viruses

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The nucleocytoplasmic large DNA viruses or NCLDV refers to the five families of large eukaryotic DNA viruses:

  1. Poxviridae
  2. Asfarviridae
  3. Iridoviridae
  4. Phycodnaviridae
  5. Coccolithoviridae

The Mimivirus is also counted as a NCLDV.

[edit] Reasons for NCLDV Grouping

All have both common and unique features of genomic DNA and virion structure. It remains uncertain whether the similarities of different families of this grouping of NCLDV are due to independent recruitment of the same or related host genes during viral replication or if they simply share a common viral ancestor, although the latter is under heavy scrutiny and controversy [1]

[edit] Literature

  1. ^ Lakshminarayan M. Iyer, L. Aravind, and Eugene V. Koonin. "Common Origin of Four Diverse Families of Large Eukaryotic DNA Viruses." Journal of Virology, December 2001, p. 11720-11734, Vol. 75, No. 23.
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