NRAP

From Wikipedia, the free encyclopedia

Nebulin-related anchoring protein

Identifiers

External IDs

OMIM: 602873 MGI: 1098765 HomoloGene: 4499

Gene ontology
Molecular Function:	• actin binding • protein binding • zinc ion binding • metal ion binding • muscle alpha-actinin binding
Cellular Component:	• fascia adherens • muscle tendon junction
Biological Process:	• biological_process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006175 (mRNA)
NP_006166 (protein)

NM_008733 (mRNA)
NP_032759 (protein)

Location

Chr 10: 115.34 - 115.41 Mb

Chr 19: 56.37 - 56.44 Mb

Pubmed search

[1]

[2]

Nebulin-related anchoring protein, also known as NRAP, is a human gene.^[1]

[edit] References

^ Entrez Gene: NRAP nebulin-related anchoring protein.

[edit] Further reading

Lanfranchi G, Muraro T, Caldara F, et al. (1996). "Identification of 4370 expressed sequence tags from a 3'-end-specific cDNA library of human skeletal muscle by DNA sequencing and filter hybridization.". Genome Res. 6 (1): 35–42. PMID 8681137.
Luo G, Zhang JQ, Nguyen TP, et al. (1997). "Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein of striated muscle.". Cell Motil. Cytoskeleton 38 (1): 75–90. doi:10.1002/(SICI)1097-0169(1997)38:1<75::AID-CM7>3.0.CO;2-G. PMID 9295142.
Luo G, Leroy E, Kozak CA, et al. (1997). "Mapping of the gene (NRAP) encoding N-RAP in the mouse and human genomes.". Genomics 45 (1): 229–32. doi:10.1006/geno.1997.4917. PMID 9339382.
Luo G, Herrera AH, Horowits R (1999). "Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.". Biochemistry 38 (19): 6135–43. doi:10.1021/bi982395t. PMID 10320340.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Mohiddin SA, Lu S, Cardoso JP, et al. (2004). "Genomic organization, alternative splicing, and expression of human and mouse N-RAP, a nebulin-related LIM protein of striated muscle.". Cell Motil. Cytoskeleton 55 (3): 200–12. doi:10.1002/cm.10123. PMID 12789664.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.
Witt SH, Granzier H, Witt CC, Labeit S (2005). "MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination.". J. Mol. Biol. 350 (4): 713–22. doi:10.1016/j.jmb.2005.05.021. PMID 15967462.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.