NPW

From Wikipedia, the free encyclopedia


Neuropeptide W
Identifiers
Symbol(s) NPW; PPL8; PPNPW
External IDs OMIM: 607997 MGI: 2685781 HomoloGene: 17727
Orthologs
Human Mouse
Entrez 283869 381073
Ensembl ENSG00000183971 ENSMUSG00000071230
Uniprot Q8N729 n/a
Refseq XM_496111 (mRNA)
XP_496111 (protein)		 XM_354994 (mRNA)
XP_354994 (protein)
Location Chr 16: 2.01 - 2.01 Mb Chr 17: 24.39 - 24.39 Mb
Pubmed search [1] [2]

Neuropeptide W, also known as NPW, is a human gene.[1]

Neuropeptide W (NPW) is an endogenous peptide ligand for GPR8 (MIM 600731), a G protein-coupled receptor.[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: NPW neuropeptide W.

[edit] Further reading

  • Singh G, Davenport AP (2006). "Neuropeptide B and W: neurotransmitters in an emerging G-protein-coupled receptor system.". Br. J. Pharmacol. 148 (8): 1033-41. doi:10.1038/sj.bjp.0706825. PMID 16847439. 
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548. 
  • Fujii R, Yoshida H, Fukusumi S, et al. (2002). "Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7.". J. Biol. Chem. 277 (37): 34010-6. doi:10.1074/jbc.M205883200. PMID 12118011. 
  • Shimomura Y, Harada M, Goto M, et al. (2002). "Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8.". J. Biol. Chem. 277 (39): 35826-32. doi:10.1074/jbc.M205337200. PMID 12130646. 
  • Brezillon S, Lannoy V, Franssen JD, et al. (2003). "Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8.". J. Biol. Chem. 278 (2): 776-83. doi:10.1074/jbc.M206396200. PMID 12401809. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Tanaka H, Yoshida T, Miyamoto N, et al. (2003). "Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8.". Proc. Natl. Acad. Sci. U.S.A. 100 (10): 6251-6. doi:10.1073/pnas.0837789100. PMID 12719537. 
  • Mondal MS, Yamaguchi H, Date Y, et al. (2003). "A role for neuropeptide W in the regulation of feeding behavior.". Endocrinology 144 (11): 4729-33. doi:10.1210/en.2003-0536. PMID 12959997. 
  • Mazzocchi G, Rebuffat P, Ziolkowska A, et al. (2005). "G protein receptors 7 and 8 are expressed in human adrenocortical cells, and their endogenous ligands neuropeptides B and w enhance cortisol secretion by activating adenylate cyclase- and phospholipase C-dependent signaling cascades.". J. Clin. Endocrinol. Metab. 90 (6): 3466-71. doi:10.1210/jc.2004-2132. PMID 15797961. 
  • Andreis PG, Rucinski M, Neri G, et al. (2006). "Neuropeptides B and W enhance the growth of human adrenocortical carcinoma-derived NCI-H295 cells by exerting MAPK p42/p44-mediated proliferogenic and antiapoptotic effects.". Int. J. Mol. Med. 16 (6): 1021-8. PMID 16273281. 
  • Mondal MS, Yamaguchi H, Date Y, et al. (2006). "Neuropeptide W is present in antral G cells of rat, mouse, and human stomach.". J. Endocrinol. 188 (1): 49-57. doi:10.1677/joe.1.06195. PMID 16394174. 
 This article on a gene on chromosome 16 is a stub. You can help Wikipedia by expanding it.