NPTX2

From Wikipedia, the free encyclopedia

Neuronal pentraxin II

Identifiers

NPTX2; NARP; NP-II; NP2

External IDs

OMIM: 600750 MGI: 1858209 HomoloGene: 1892

Gene ontology
Molecular Function:	• molecular_function • calcium ion binding • sugar binding
Cellular Component:	• cellular_component
Biological Process:	• synaptic transmission

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002523 (mRNA)
NP_002514 (protein)

NM_016789 (mRNA)
NP_058069 (protein)

Location

Chr 7: 98.08 - 98.1 Mb

Chr 5: 144.8 - 144.81 Mb

Pubmed search

[1]

[2]

Neuronal pentraxin II, also known as NPTX2, is a human gene.^[1]

[edit] References

^ Entrez Gene: NPTX2 neuronal pentraxin II.

[edit] Further reading

Park JK, Ryu JK, Lee KH, et al. (2007). "Quantitative analysis of NPTX2 hypermethylation is a promising molecular diagnostic marker for pancreatic cancer.". Pancreas 35 (3): e9-15. doi:10.1097/MPA.0b013e318153fa42. PMID 17895837.
Marui T, Koishi S, Funatogawa I, et al. (2007). "No association between the neuronal pentraxin II gene polymorphism and autism.". Prog. Neuropsychopharmacol. Biol. Psychiatry 31 (4): 940-3. doi:10.1016/j.pnpbp.2007.02.016. PMID 17408830.
Poulsen TT, Pedersen N, Perin MS, et al. (2006). "Specific sensitivity of small cell lung cancer cell lines to the snake venom toxin taipoxin.". Lung Cancer 50 (3): 329-37. doi:10.1016/j.lungcan.2005.06.011. PMID 16115696.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157-64. doi:10.1038/nature01782. PMID 12853948.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Kirkpatrick LL, Matzuk MM, Dodds DC, Perin MS (2000). "Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2.". J. Biol. Chem. 275 (23): 17786-92. doi:10.1074/jbc.M002254200. PMID 10748068.
Dodds DC, Omeis IA, Cushman SJ, et al. (1997). "Neuronal pentraxin receptor, a novel putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2 and taipoxin-associated calcium-binding protein 49.". J. Biol. Chem. 272 (34): 21488-94. PMID 9261167.
Hsu YC, Perin MS (1996). "Human neuronal pentraxin II (NPTX2): conservation, genomic structure, and chromosomal localization.". Genomics 28 (2): 220-7. doi:10.1006/geno.1995.1134. PMID 8530029.