NOS1

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Nitric oxide synthase 1 (neuronal)
PDB rendering based on 1b8q.
Available structures: 1b8q, 1f20, 1k2r, 1k2s, 1k2t, 1k2u, 1lzx, 1lzz, 1m00, 1mmv, 1mmw, 1om4, 1om5, 1p6h, 1p6i, 1p6j, 1p6k, 1qau, 1qav, 1qw6, 1qwc, 1rs6, 1rs7, 1tll, 1vag, 1zvi, 1zvl, 1zzq, 1zzr, 1zzu, 2g6h, 2g6i, 2g6j, 2g6k, 2g6l, 2g6m, 2g6n, 2hx3, 2hx4
Identifiers
Symbol(s)	NOS1; IHPS1; NOS
External IDs	OMIM: 163731 MGI: 97360 HomoloGene: 37327
Gene ontology Molecular Function: • nitric-oxide synthase activity • iron ion binding • calmodulin binding • electron carrier activity • FMN binding • oxidoreductase activity • heme binding • metal ion binding • FAD binding • NADP binding Cellular Component: • membrane fraction • synapse Biological Process: • electron transport • nitric oxide biosynthetic process • striated muscle contraction • synaptic transmission
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	4842	18125
Ensembl	ENSG00000089250	ENSMUSG00000029361
Uniprot	P29475	Q9JJ30
Refseq	NM_000620 (mRNA) NP_000611 (protein)	XM_992536 (mRNA) XP_997630 (protein)
Location	Chr 12: 116.14 - 116.28 Mb	Chr 5: 118.1 - 118.22 Mb
Pubmed search	[1]	[2]

Nitric oxide synthase 1 (neuronal), also known as NOS1, is a human gene.

[edit] See also

• Nitric oxide synthase

[edit] Further reading

v • d • e Oxidoreductases: dioxygenases, including steroid hydroxylases (EC 1.14) 1.14.11 - 2-oxoglutarate Prolyl hydroxylase - Lysyl hydroxylase 1.14.13 - NADH or NADPH Flavin-containing monooxygenase - Nitric oxide synthase (NOS1, NOS2A, NOS3) - Cholesterol 7 alpha-hydroxylase - Methane monooxygenase - 3A4 -51A1 1.14.14 - reduced flavin or flavoprotein 19A1 - 2D6 - 2E1 1.14.15 - reduced iron-sulfur protein 11B1 - 11B2 - 11A1 1.14.16 - reduced pteridine Phenylalanine hydroxylase - Tyrosine hydroxylase - Tryptophan hydroxylase 1.14.17 - reduced ascorbate Dopamine beta hydroxylase 1.14.18-19 - other Tyrosinase - Stearoyl-CoA desaturase-1 1.14.99 - miscellaneous Cyclooxygenase - Heme oxygenase (HMOX1) - Squalene monooxygenase - 17A1 - 21A2

v • d • e Metabolism: amino acid metabolism - neurotransmitter enzymes histidine→histamine anabolism: Histidine decarboxylase catabolism: Histamine N-methyltransferase - Amine oxidase tyrosine→dopamine→epinephrine anabolism: Tyrosine hydroxylase - Aromatic L-amino acid decarboxylase - Dopamine beta hydroxylase - Phenylethanolamine N-methyltransferase catabolism: Catechol-O-methyl transferase - Monoamine oxidase glutamate→GABA anabolism: Glutamate decarboxylase catabolism: 4-aminobutyrate aminotransferase tryptophan→serotonin→melatonin Tryptophan hydroxylase - Aromatic L-amino acid decarboxylase - Acetylserotonin O-methyltransferase arginine→NO Nitric oxide synthase (NOS1, NOS2A, NOS3) see also intermediates