Norzoanthamine
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| Norzoanthamine | |
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| IUPAC name | (4aS,6aS,7S,7aS,9aS,11S,13R,15aR,16aS,16bR)-
1,4a,5,7,7a,8,9,11,12,13,14,16,16a,16b- Tetradecahydro-2,7,7a,11,16a- pentamethyl-4H,10H-9a,13-epoxy-15a,7-(epoxyethano) azepino[1,2-a]naphtho[2,1-g]quinoline-4,6,18(6aH)-trione |
| Other names | Norzoanthamine |
| Identifiers | |
| CAS number | [164991-65-5] |
| Properties | |
| Molecular formula | C29H39NO5 |
| Molar mass | 481.62 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Norzoanthamine is a new alkaloid found in Zoanthus species (Class Anthozoa), a kind of sea anemones.
Norzoanthamine has been shown to suppress the loss of bone weight and strength in mice; that could lead to a treatment for osteoporosis. Some derivatives of norzoanthamine also suppress development of some kind of leukemia cell lines and human platelet aggregation.
A laboratory synthesis of this compound was developed in 2004.[1]
[edit] References
- ^ Masaaki Miyashita, Minoru Sasaki, Izumi Hattori, Mio Sakai, Keiji Tanino. "Total Synthesis of Norzoanthamine" Science 23 July 2004: Vol. 305. no. 5683, pp. 495 - 499 doi:10.1126/science.1098851
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