NOL1

From Wikipedia, the free encyclopedia

Nucleolar protein 1, 120kDa

Identifiers

NOL1; p120; MGC117384; MGC149287; MGC149288; NOP120; NSUN1

External IDs

OMIM: 164031 MGI: 107891 HomoloGene: 6817

Gene ontology
Molecular Function:	• protein binding • methyltransferase activity • transferase activity
Cellular Component:	• nucleus • nucleolus
Biological Process:	• regulation of progression through cell cycle • positive regulation of cell proliferation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_001033714 (mRNA)
NP_001028886 (protein)

XM_982076 (mRNA)
XP_987170 (protein)

Location

Chr 12: 6.54 - 6.55 Mb

Chr 6: 125.1 - 125.11 Mb

Pubmed search

[1]

[2]

Nucleolar protein 1, 120kDa, also known as NOL1, is a human gene.^[1]

[edit] References

^ Entrez Gene: NOL1 nucleolar protein 1, 120kDa.

[edit] Further reading

Busch H (1990). "The final common pathway of cancer.". Cancer Res. 50 (16): 4830–8. PMID 2199030.
Valdez BC, Perlaky L, Saijo Y, et al. (1992). "A region of antisense RNA from human p120 cDNA with high homology to mouse p120 cDNA inhibits NIH 3T3 proliferation.". Cancer Res. 52 (20): 5681–6. PMID 1394192.
Larson RG, Henning D, Haidar MA, et al. (1990). "Genomic structure of the human proliferating cell nucleolar protein P120.". Cancer Commun. 2 (2): 63–71. PMID 2372471.
Fonagy A, Henning D, Jhiang S, et al. (1990). "Cloning of the cDNA and sequence of the human proliferating-cell nucleolar protein P120.". Cancer Commun. 1 (4): 243–51. PMID 2576976.
Freeman JW, Busch RK, Gyorkey F, et al. (1988). "Identification and characterization of a human proliferation-associated nucleolar antigen with a molecular weight of 120,000 expressed in early G1 phase.". Cancer Res. 48 (5): 1244–51. PMID 3422591.
Baens M, Chaffanet M, Aerssens J, et al. (1994). "Assignment of the gene for the human proliferating cell nucleolar protein P120 (NOL1) to chromosome 12p13 by fluorescence in situ hybridization and polymerase chain reaction with somatic cell hybrids.". Genomics 21 (1): 296–7. doi:10.1006/geno.1994.1267. PMID 8088812.
Valdez BC, Perlaky L, Henning D, et al. (1994). "Identification of the nuclear and nucleolar localization signals of the protein p120. Interaction with translocation protein B23.". J. Biol. Chem. 269 (38): 23776–83. PMID 8089149.
Jallal B, Mossie K, Vasiloudis G, et al. (1997). "The receptor-like protein-tyrosine phosphatase DEP-1 is constitutively associated with a 64-kDa protein serine/threonine kinase.". J. Biol. Chem. 272 (18): 12158–63. PMID 9115287.
Ren Y, Busch RK, Perlaky L, Busch H (1998). "The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120.". Eur. J. Biochem. 253 (3): 734–42. PMID 9654073.
Colombo E, Marine JC, Danovi D, et al. (2002). "Nucleophosmin regulates the stability and transcriptional activity of p53.". Nat. Cell Biol. 4 (7): 529–33. doi:10.1038/ncb814. PMID 12080348.
Holsinger LJ, Ward K, Duffield B, et al. (2002). "The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn).". Oncogene 21 (46): 7067–76. doi:10.1038/sj.onc.1205858. PMID 12370829.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus.". Mol. Biol. Cell 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMID 12429849.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMID 16565220.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.