NME3

From Wikipedia, the free encyclopedia

Non-metastatic cells 3, protein expressed in

PDB rendering based on 1zs6.

Available structures: 1zs6

Identifiers

Symbol(s)

NME3; DR-nm23; KIAA0516; c371H6.2

External IDs

OMIM: 601817 MGI: 1930182 HomoloGene: 20562

Gene ontology
Molecular Function:	• nucleotide binding • magnesium ion binding • nucleoside diphosphate kinase activity • ATP binding • kinase activity • transferase activity
Biological Process:	• GTP biosynthetic process • UTP biosynthetic process • CTP biosynthetic process • apoptosis • induction of apoptosis • nucleotide metabolic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002513 (mRNA)
NP_002504 (protein)

NM_019730 (mRNA)
NP_062704 (protein)

Location

Chr 16: 1.76 - 1.76 Mb

Chr 17: 24.62 - 24.63 Mb

Pubmed search

[1]

[2]

Non-metastatic cells 3, protein expressed in, also known as NME3, is a human gene.^[1]

[edit] References

^ Entrez Gene: NME3 non-metastatic cells 3, protein expressed in.

[edit] Further reading

Venturelli D, Martinez R, Melotti P, et al. (1995). "Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells.". Proc. Natl. Acad. Sci. U.S.A. 92 (16): 7435–9. PMID 7638209.
Martinez R, Venturelli D, Perrotti D, et al. (1997). "Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family.". Cancer Res. 57 (6): 1180–7. PMID 9067290.
Negroni A, Venturelli D, Tanno B, et al. (2000). "Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis.". Cell Death Differ. 7 (9): 843–50. doi:10.1038/sj.cdd.4400720. PMID 11042679.
Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.". Hum. Mol. Genet. 10 (4): 339–52. PMID 11157797.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Sheffler DJ, Kroeze WK, Garcia BG, et al. (2006). "p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling.". Proc. Natl. Acad. Sci. U.S.A. 103 (12): 4717–22. doi:10.1073/pnas.0600585103. PMID 16537434.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Carinci F, Arcelli D, Lo Muzio L, et al. (2007). "Molecular classification of nodal metastasis in primary larynx squamous cell carcinoma.". Translational research : the journal of laboratory and clinical medicine 150 (4): 233–45. doi:10.1016/j.trsl.2007.03.011. PMID 17900511.