NISCH

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Nischarin
Identifiers
Symbol(s) NISCH; FLJ14425; FLJ40413; FLJ90519; I-1; IRAS; KIAA0975
External IDs HomoloGene: 5201
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 11188 n/a
Ensembl ENSG00000010322 n/a
Refseq NM_007184 (mRNA)
NP_009115 (protein)		 n/a (mRNA)
n/a (protein)
Location Chr 3: 52.46 - 52.5 Mb n/a
Pubmed search [1] n/a

Nischarin, also known as NISCH, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: NISCH nischarin.

[edit] Further reading

  • Ivanov TR, Jones JC, Dontenwill M, et al. (1999). "Characterization of a partial cDNA clone detected by imidazoline receptor-selective antisera.". J. Auton. Nerv. Syst. 72 (2-3): 98-110. PMID 9851558. 
  • Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63-70. PMID 10231032. 
  • Piletz JE, Ivanov TR, Sharp JD, et al. (2000). "Imidazoline receptor antisera-selected (IRAS) cDNA: cloning and characterization.". DNA Cell Biol. 19 (6): 319-29. doi:10.1089/10445490050043290. PMID 10882231. 
  • Sano H, Liu SC, Lane WS, et al. (2002). "Insulin receptor substrate 4 associates with the protein IRAS.". J. Biol. Chem. 277 (22): 19439-47. doi:10.1074/jbc.M111838200. PMID 11912194. 
  • El-Ayoubi R, Gutkowska J, Regunathan S, Mukaddam-Daher S (2002). "Imidazoline receptors in the heart: characterization, distribution, and regulation.". J. Cardiovasc. Pharmacol. 39 (6): 875-83. PMID 12021582. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Edwards L, Ernsberger P (2003). "The I(1)-imidazoline receptor in PC12 pheochromocytoma cells reverses NGF-induced ERK activation and induces MKP-2 phosphatase.". Brain Res. 980 (1): 71-9. PMID 12865160. 
  • Dontenwill M, Pascal G, Piletz JE, et al. (2004). "IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells.". Cell Death Differ. 10 (8): 933-5. doi:10.1038/sj.cdd.4401275. PMID 12868002. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Dontenwill M, Piletz JE, Chen M, et al. (2004). "IRAS is an anti-apoptotic protein.". Ann. N. Y. Acad. Sci. 1009: 400-12. PMID 15028619. 
  • Piletz JE, Deleersnijder W, Roth BL, et al. (2004). "IRAS splice variants.". Ann. N. Y. Acad. Sci. 1009: 419-26. PMID 15028621. 
  • Chen MJ, Zhu HE, Piletz JE (2004). "Intracellular effect of imidazoline receptor on alpha(2A)-noradrenergic receptor.". Ann. N. Y. Acad. Sci. 1009: 427-38. PMID 15028622. 
  • Zhu H, Hayes J, Chen M, et al. (2004). "Relationship between platelet imidazoline receptor-binding peptides and candidate imidazoline-1 receptor, IRAS.". Ann. N. Y. Acad. Sci. 1009: 439-46. PMID 15028623. 
  • Lim KP, Hong W (2005). "Human Nischarin/imidazoline receptor antisera-selected protein is targeted to the endosomes by a combined action of a PX domain and a coiled-coil region.". J. Biol. Chem. 279 (52): 54770-82. doi:10.1074/jbc.M411315200. PMID 15475348. 
  • Li F, Wu N, Su RB, et al. (2006). "Involvement of phosphatidylcholine-selective phospholipase C in activation of mitogen-activated protein kinase pathways in imidazoline receptor antisera-selected protein.". J. Cell. Biochem. 98 (6): 1615-28. doi:10.1002/jcb.20806. PMID 16598778. 
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