Talk:Neurotrophin
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There have been reports in the media about the role of neurotrophins in romantic feelings. [1] - Karl Stas 19:56, 28 November 2005 (UTC)
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[edit] Query
From the article: "Despite its name, BDNF is actually found in a range of tissue and cell types, not just the brain. Expression can be seen in the retina, the CNS, motor neurons, the kidneys, the prostate and post-katiemorgan circuit"
Is there really such a thing as a post-katiemorgan circuit? I couldn't find any sign of it in a Google search but I did find links to people named Katie Morgan, one of whom appears to be a "porn star"...
—The preceding unsigned comment was added by 88.104.233.164 (talk) 20:27, 23 January 2007 (UTC).
[edit] Incorrect
There are much more neurotrophins then mentioned in this article. The ones mentioned here are from the NGF-family only, but there are others like glial cell derived neurotrophic factor (GDNF) and ciliary neurotrophic factor (CNTF). Unfortunately, I don't know enough about those. Methoxyroxy 16:06, 16 June 2006 (UTC)
[edit] I do
I can add in a discussion on GDNF, CNTF, etc...
The question is how broad one should go. For example, IGF-1 is neuro-protective, but most people would not classify it as a "neurotrophin" despite the fact that it has "neurotrophic factor activity."
Gacggt 22:56, 17 June 2006 (UTC)
[edit] Needs Sourcing
Article doesn't reference sources for the information it lists. Once sources/references are added, the tag can be removed.--Isotope23 18:40, 27 June 2006 (UTC)
I added references for three review articles, which both confirm the information given so far, and which give extensive further sourcing. Therefore I removed the tag.Gacggt 18:49, 27 June 2006 (UTC)
- Excellent... thanks.--Isotope23 12:27, 28 June 2006 (UTC)
[edit] neurones or tissue, "target neurones"?
THe beginning needs more specifity and possibly more precision. The sense I get is that the cells a neurone connects to protect it from destroying itself by producing trophic factors. "Target neurones" doesn't seem to be quite th eright phrase, at least on that basis. Midgley 17:09, 8 July 2006 (UTC)
[edit] Redirects
I find it strange that the "main article" for Neurotrophin-4 is NT-4, whereas the main articles for brain-derived neurotrophic factor, neurotrophin-3, nerve growth factor, etc. all point to "main" articles titled with their full name. If no one objects, I would suggest pointing to "Neurotrophin-4" instead of NT-4 (and, of course, moving all relevant information to that article). Jamestttgrays (talk) 03:51, 14 May 2008 (UTC)
