NEO1

From Wikipedia, the free encyclopedia

Neogenin homolog 1 (chicken)

PDB rendering based on 1x5f.

Available structures: 1x5f, 1x5g, 1x5h, 1x5i, 1x5j, 1x5k

Identifiers

Symbol(s)

NEO1; HsT17534; NGN

External IDs

OMIM: 601907 MGI: 1097159 HomoloGene: 1870

Gene ontology
Molecular Function:	• receptor activity • protein binding • transcription regulator activity • cadherin binding
Cellular Component:	• plasma membrane • integral to plasma membrane • integral to membrane
Biological Process:	• cell motility • cell adhesion • cell-cell signaling • multicellular organismal development • myoblast fusion • regulation of transcription

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002499 (mRNA)
NP_002490 (protein)

NM_001042752 (mRNA)
NP_001036217 (protein)

Location

Chr 15: 71.13 - 71.38 Mb

Chr 9: 58.67 - 58.83 Mb

Pubmed search

[1]

[2]

Neogenin homolog 1 (chicken), also known as NEO1, is a human gene.^[1]

[edit] References

^ Entrez Gene: NEO1 neogenin homolog 1 (chicken).

[edit] Further reading

Vielmetter J, Kayyem JF, Roman JM, Dreyer WJ (1995). "Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer.". J. Cell Biol. 127 (6 Pt 2): 2009–20. PMID 7806578.
Keino-Masu K, Masu M, Hinck L, et al. (1996). "Deleted in Colorectal Cancer (DCC) encodes a netrin receptor.". Cell 87 (2): 175–85. PMID 8861902.
Meyerhardt JA, Look AT, Bigner SH, Fearon ER (1997). "Identification and characterization of neogenin, a DCC-related gene.". Oncogene 14 (10): 1129–36. doi:10.1038/sj.onc.1200935. PMID 9121761.
Vielmetter J, Chen XN, Miskevich F, et al. (1997). "Molecular characterization of human neogenin, a DCC-related protein, and the mapping of its gene (NEO1) to chromosomal position 15q22.3-q23.". Genomics 41 (3): 414–21. doi:10.1006/geno.1997.4688. PMID 9169140.
Wang H, Copeland NG, Gilbert DJ, et al. (1999). "Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors.". J. Neurosci. 19 (12): 4938–47. PMID 10366627.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Srinivasan K, Strickland P, Valdes A, et al. (2003). "Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis.". Dev. Cell 4 (3): 371–82. PMID 12636918.
Ho SM, Lau KM, Mok SC, Syed V (2003). "Profiling follicle stimulating hormone-induced gene expression changes in normal and malignant human ovarian surface epithelial cells.". Oncogene 22 (27): 4243–56. doi:10.1038/sj.onc.1206437. PMID 12833147.
Matsunaga E, Tauszig-Delamasure S, Monnier PP, et al. (2004). "RGM and its receptor neogenin regulate neuronal survival.". Nat. Cell Biol. 6 (8): 749–55. doi:10.1038/ncb1157. PMID 15258591.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Ren XR, Ming GL, Xie Y, et al. (2005). "Focal adhesion kinase in netrin-1 signaling.". Nat. Neurosci. 7 (11): 1204–12. doi:10.1038/nn1330. PMID 15494733.
Lee JE, Kim HJ, Bae JY, et al. (2006). "Neogenin expression may be inversely correlated to the tumorigenicity of human breast cancer.". BMC Cancer 5: 154. doi:10.1186/1471-2407-5-154. PMID 16324219.
Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.