NEK9

From Wikipedia, the free encyclopedia

NIMA (never in mitosis gene a)- related kinase 9

Identifiers

NEK9; DKFZp434D0935; MGC138306; MGC16714; NERCC; NERCC1; Nek8

External IDs

OMIM: 609798 MGI: 2387995 HomoloGene: 13222

Gene ontology
Molecular Function:	• nucleotide binding • magnesium ion binding • protein serine/threonine kinase activity • ATP binding • transferase activity
Cellular Component:	• nucleus
Biological Process:	• protein amino acid phosphorylation • cell cycle • mitosis • cell division

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_033116 (mRNA)
NP_149107 (protein)

XM_994284 (mRNA)
XP_999378 (protein)

Location

Chr 14: 74.62 - 74.66 Mb

Chr 12: 86.19 - 86.23 Mb

Pubmed search

[1]

[2]

NIMA (never in mitosis gene a)- related kinase 9, also known as NEK9, is a human gene.^[1]

[edit] References

^ Entrez Gene: NEK9 NIMA (never in mitosis gene a)- related kinase 9.

[edit] Further reading

Pelka P, Scimè A, Mandalfino C, et al. (2007). "Adenovirus E1A proteins direct subcellular redistribution of Nek9, a NimA-related kinase.". J. Cell. Physiol. 212 (1): 13–25. doi:10.1002/jcp.20983. PMID 17443675.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
Wissing J, Jänsch L, Nimtz M, et al. (2007). "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.". Mol. Cell Proteomics 6 (3): 537–47. doi:10.1074/mcp.T600062-MCP200. PMID 17192257.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Bowers AJ, Boylan JF (2004). "Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors.". Gene 328: 135–42. doi:10.1016/j.gene.2003.12.002. PMID 15019993.
Tan BC, Lee SC (2004). "Nek9, a novel FACT-associated protein, modulates interphase progression.". J. Biol. Chem. 279 (10): 9321–30. doi:10.1074/jbc.M311477200. PMID 14660563.
Belham C, Roig J, Caldwell JA, et al. (2003). "A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases.". J. Biol. Chem. 278 (37): 34897–909. doi:10.1074/jbc.M303663200. PMID 12840024.
Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14.". Nature 421 (6923): 601–7. doi:10.1038/nature01348. PMID 12508121.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Roig J, Mikhailov A, Belham C, Avruch J (2002). "Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression.". Genes Dev. 16 (13): 1640–58. doi:10.1101/gad.972202. PMID 12101123.
Ohara O, Nagase T, Mitsui G, et al. (2003). "Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method.". DNA Res. 9 (2): 47–57. PMID 12056414.
Holland PM, Milne A, Garka K, et al. (2002). "Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2.". J. Biol. Chem. 277 (18): 16229–40. doi:10.1074/jbc.M108662200. PMID 11864968.