NCOA4
From Wikipedia, the free encyclopedia
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Nuclear receptor coactivator 4
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| Identifiers | ||||||||||||||
| Symbol(s) | NCOA4; ARA70; DKFZp762E1112; ELE1; PTC3; RFG | |||||||||||||
| External IDs | OMIM: 601984 MGI: 1350932 HomoloGene: 38052 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 8031 | 27057 | ||||||||||||
| Ensembl | ENSG00000138293 | ENSMUSG00000056234 | ||||||||||||
| Uniprot | Q13772 | n/a | ||||||||||||
| Refseq | NM_005437 (mRNA) NP_005428 (protein) |
NM_001033988 (mRNA) NP_001029160 (protein) |
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| Location | Chr 10: 51.24 - 51.26 Mb | Chr 14: 31 - 31.01 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Nuclear receptor coactivator 4, also known as NCOA4, is a human gene.[1]
[edit] References
[edit] See also
[edit] Further reading
- Minoletti F, Butti MG, Coronelli S, et al. (1995). "The two genes generating RET/PTC3 are localized in chromosomal band 10q11.2.". Genes Chromosomes Cancer 11 (1): 51–7. PMID 7529046.
- Jhiang SM, Smanik PA, Mazzaferri EL (1994). "Development of a single-step duplex RT-PCR detecting different forms of ret activation, and identification of the third form of in vivo ret activation in human papillary thyroid carcinoma.". Cancer Lett. 78 (1-3): 69–76. PMID 8180971.
- Bongarzone I, Butti MG, Coronelli S, et al. (1994). "Frequent activation of ret protooncogene by fusion with a new activating gene in papillary thyroid carcinomas.". Cancer Res. 54 (11): 2979–85. PMID 8187085.
- Santoro M, Dathan NA, Berlingieri MT, et al. (1994). "Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma.". Oncogene 9 (2): 509–16. PMID 8290261.
- Yeh S, Chang C (1996). "Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.". Proc. Natl. Acad. Sci. U.S.A. 93 (11): 5517–21. PMID 8643607.
- Bongarzone I, Butti MG, Fugazzola L, et al. (1997). "Comparison of the breakpoint regions of ELE1 and RET genes involved in the generation of RET/PTC3 oncogene in sporadic and in radiation-associated papillary thyroid carcinomas.". Genomics 42 (2): 252–9. doi:. PMID 9192845.
- Miyamoto H, Yeh S, Wilding G, Chang C (1998). "Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells.". Proc. Natl. Acad. Sci. U.S.A. 95 (13): 7379–84. PMID 9636157.
- Alen P, Claessens F, Schoenmakers E, et al. (1999). "Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1alpha with multiple steroid receptors and identification of an internally deleted ELE1beta isoform.". Mol. Endocrinol. 13 (1): 117–28. PMID 9892017.
- Kang HY, Yeh S, Fujimoto N, Chang C (1999). "Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor.". J. Biol. Chem. 274 (13): 8570–6. PMID 10085091.
- Yeh S, Lin HK, Kang HY, et al. (1999). "From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells.". Proc. Natl. Acad. Sci. U.S.A. 96 (10): 5458–63. PMID 10318905.
- Heinlein CA, Ting HJ, Yeh S, Chang C (1999). "Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma.". J. Biol. Chem. 274 (23): 16147–52. PMID 10347167.
- Gao T, Brantley K, Bolu E, McPhaul MJ (1999). "RFG (ARA70, ELE1) interacts with the human androgen receptor in a ligand-dependent fashion, but functions only weakly as a coactivator in cotransfection assays.". Mol. Endocrinol. 13 (10): 1645–56. PMID 10517667.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:. PMID 11256614.
- Lin HK, Yeh S, Kang HY, Chang C (2001). "Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor.". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7200–5. doi:. PMID 11404460.
- Basolo F, Giannini R, Monaco C, et al. (2002). "Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma.". Am. J. Pathol. 160 (1): 247–54. PMID 11786418.
- Zhou ZX, He B, Hall SH, et al. (2002). "Domain interactions between coregulator ARA(70) and the androgen receptor (AR).". Mol. Endocrinol. 16 (2): 287–300. PMID 11818501.
- Thin TH, Kim E, Yeh S, et al. (2002). "Mutations in the helix 3 region of the androgen receptor abrogate ARA70 promotion of 17beta-estradiol-induced androgen receptor transactivation.". J. Biol. Chem. 277 (39): 36499–508. doi:. PMID 12068007.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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