NBR2

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neighbor of BRCA1 gene 2
Identifiers
Symbol NBR2
Entrez 10230
HUGO 20691
RefSeq NM_005821
Other data
Locus Chr. 17 q21

NBR2 is a gene best known for its location near the breast cancer associated gene BRCA1.[1] Like BRCA1, NBR2 has been a subject of research,[2] but links to breast cancer are currently inconclusive.

[edit] References

  1. ^ Xu CF, Brown MA, Nicolai H, Chambers JA, Griffiths BL, Solomon E (1997). "Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene". Hum. Mol. Genet. 6 (7): 1057–62. PMID 9215675. 
  2. ^ Auriol E, Billard LM, Magdinier F, Dante R (2005). "Specific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus". Nucleic Acids Res. 33 (13): 4243–54. doi:10.1093/nar/gki729. PMID 16052033.