Naringenin 8-dimethylallyltransferase

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In enzymology, a naringenin 8-dimethylallyltransferase (EC 2.5.1.70) is an enzyme that catalyzes the chemical reaction

dimethylallyl diphosphate + (-)-(2S)-naringenin $\rightleftharpoons$ diphosphate + sophoraflavanone B

Thus, the two substrates of this enzyme are dimethylallyl diphosphate and (-)-(2S)-naringenin, whereas its two products are diphosphate and sophoraflavanone B.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is dimethylallyl-diphosphate:naringenin 8-dimethylallyltransferase. This enzyme is also called N8DT.

[edit] References

IUBMB entry for 2.5.1.70
BRENDA references for 2.5.1.70 (Recommended.)
PubMed references for 2.5.1.70
PubMed Central references for 2.5.1.70
Google Scholar references for 2.5.1.70
Yamamoto H, Senda M, Inoue K (2000). "Flavanone 8-dimethylallyltransferase in Sophora flavescens cell suspension cultures". Phytochemistry. 54: 649–55. doi:10.1016/S0031-9422(00)00198-9. PMID 10975499.
Zhao P, Inoue K, Kouno I, Yamamoto H (2003). "Characterization of leachianone G 2"-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait cell suspension cultures". Plant. Physiol. 133: 1306–13. doi:10.1104/pp.103.025213. PMID 14551337.