Nalpha-benzyloxycarbonylleucine hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a Nalpha-benzyloxycarbonylleucine hydrolase (EC 3.5.1.64) is an enzyme that catalyzes the chemical reaction

Nalpha-benzyloxycarbonyl-L-leucine + H₂O benzyl alcohol + CO₂ + L-leucine

Thus, the two substrates of this enzyme are Nalpha-benzyloxycarbonyl-L-leucine and H₂O, whereas its 3 products are benzyl alcohol, CO₂, and L-leucine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is Nalpha-benzyloxycarbonyl-L-leucine urethanehydrolase. Other names in common use include benzyloxycarbonylleucine hydrolase, Nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV, and alpha-N-benzyloxycarbonyl-L-leucine urethanehydrolase.

[edit] References

• IUBMB entry for 3.5.1.64
• BRENDA references for 3.5.1.64 (Recommended.)
• PubMed references for 3.5.1.64
• PubMed Central references for 3.5.1.64
• Google Scholar references for 3.5.1.64
• Matsumura E, Shin T, Murao S, Sakaguchi M and Kawano T (1985). "A novel enzyme, Nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV". Agric. Biol. Chem. 49: 3643–3645. 

[edit] External links

The CAS registry number for this enzyme class is 100630-47-5.

• IUBMB entry for 3.5.1.64

• KEGG entry for 3.5.1.64

• BRENDA entry for 3.5.1.64

• NiceZyme view of 3.5.1.64

• EC2PDB: PDB structures for 3.5.1.64

• PRIAM entry for 3.5.1.64

• PUMA2 entry for 3.5.1.64

• IntEnz: Integrated Enzyme entry for 3.5.1.64

• MetaCyc entry for 3.5.1.64

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047413: N(alpha)-benzyloxycarbonylleucine hydrolase

• AMIGO entry for GO code 0047413: N(alpha)-benzyloxycarbonylleucine hydrolase