NADPH-cytochrome-c2 reductase

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In enzymology, a NADPH---cytochrome-c2 reductase (EC 1.6.2.5) is an enzyme that catalyzes the chemical reaction

NADPH + 2 ferricytochrome c₂ NADP⁺ + H⁺ + 2 ferrocytochrome c₂

Thus, the two substrates of this enzyme are NADPH and ferricytochrome c2, whereas its 3 products are NADP⁺, H⁺, and ferrocytochrome c2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a heme protein as acceptor. The systematic name of this enzyme class is NADPH:ferricytochrome-c2 oxidoreductase. Other names in common use include cytochrome c2 reductase (reduced nicotinamide adenine dinucleotide, phosphate), cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide, and phosphate, NADPH). It employs one cofactor, FAD.

[edit] References

• IUBMB entry for 1.6.2.5
• BRENDA references for 1.6.2.5 (Recommended.)
• PubMed references for 1.6.2.5
• PubMed Central references for 1.6.2.5
• Google Scholar references for 1.6.2.5
• Sabo DJ, Orlando JA (1968). "Isolation, purification, and some properties of reduced nicotinamide adenine dinucleotide phosphate-cytochrome C2 reductase from Rhodopseudomonas spheroides". J. Biol. Chem. 243: 3742–9. PMID 4385431. 

[edit] External links

The CAS registry number for this enzyme class is 37256-32-9.

• IUBMB entry for 1.6.2.5

• KEGG entry for 1.6.2.5

• BRENDA entry for 1.6.2.5

• NiceZyme view of 1.6.2.5

• EC2PDB: PDB structures for 1.6.2.5

• PRIAM entry for 1.6.2.5

• PUMA2 entry for 1.6.2.5

• IntEnz: Integrated Enzyme entry for 1.6.2.5

• MetaCyc entry for 1.6.2.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0015047: NADPH-cytochrome-c2 reductase

• AMIGO entry for GO code 0015047: NADPH-cytochrome-c2 reductase