NAB1

From Wikipedia, the free encyclopedia

NGFI-A binding protein 1 (EGR1 binding protein 1)

Identifiers

External IDs

OMIM: 600800 MGI: 107564 HomoloGene: 4352

Gene ontology
Molecular Function:	• transcription repressor activity
Cellular Component:	• nucleus
Biological Process:	• endochondral ossification • regulation of transcription, DNA-dependent • Schwann cell differentiation • negative regulation of transcription • myelination • regulation of epidermis development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_005966 (mRNA)
NP_005957 (protein)

NM_008667 (mRNA)
NP_032693 (protein)

Location

Chr 2: 191.22 - 191.27 Mb

Chr 1: 52.4 - 52.44 Mb

Pubmed search

[1]

[2]

NGFI-A binding protein 1 (EGR1 binding protein 1), also known as NAB1, is a human gene.^[1]

[edit] References

^ Entrez Gene: NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1).

[edit] Further reading

Russo MW, Sevetson BR, Milbrandt J (1995). "Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription.". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 6873-7. PMID 7624335.
Svaren J, Sevetson BR, Apel ED, et al. (1996). "NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli.". Mol. Cell. Biol. 16 (7): 3545-53. PMID 8668170.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548.
Swirnoff AH, Apel ED, Svaren J, et al. (1998). "Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain.". Mol. Cell. Biol. 18 (1): 512-24. PMID 9418898.
Thiel G, Kaufmann K, Magin A, et al. (2000). "The human transcriptional repressor protein NAB1: expression and biological activity.". Biochim. Biophys. Acta 1493 (3): 289-301. PMID 11018254.
Qiu FH, Devchand PR, Wada K, Serhan CN (2002). "Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils.". FASEB J. 15 (14): 2736-8. doi:10.1096/fj.01-0576fje. PMID 11687510.
Venken K, Di Maria E, Bellone E, et al. (2003). "Search for mutations in the EGR2 corepressor proteins, NAB1 and NAB2, in human peripheral neuropathies.". Neurogenetics 4 (1): 37-41. PMID 12030330.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707-16. doi:10.1038/nbt971. PMID 15146197.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724-31. doi:10.1038/nature03466. PMID 15815621.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.