N6-methyl-lysine oxidase

From Wikipedia, the free encyclopedia

In enzymology, a N6-methyl-lysine oxidase (EC 1.5.3.4) is an enzyme that catalyzes the chemical reaction

N₆-methyl-L-lysine + H₂O + O₂ L-lysine + formaldehyde + H₂O₂

The 3 substrates of this enzyme are N6-methyl-L-lysine, H₂O, and O₂, whereas its 3 products are L-lysine, formaldehyde, and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with oxygen as acceptor. The systematic name of this enzyme class is N6-methyl-L-lysine:oxygen oxidoreductase (demethylating). Other names in common use include epsilon-alkyl-L-lysine:oxygen oxidoreductase, N6-methyllysine oxidase, epsilon-N-methyllysine demethylase, epsilon-alkyllysinase, and 6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating).

[edit] References

• IUBMB entry for 1.5.3.4
• BRENDA references for 1.5.3.4 (Recommended.)
• PubMed references for 1.5.3.4
• PubMed Central references for 1.5.3.4
• Google Scholar references for 1.5.3.4
• Kim S, Benoiton L and Paik WK (1964). "alpha-Alkyllysinase. Purification and properties of the enzyme". J. Biol. Chem. 239: 3790–3796. 

[edit] External links

The CAS registry number for this enzyme class is 37256-28-3.

• IUBMB entry for 1.5.3.4

• KEGG entry for 1.5.3.4

• BRENDA entry for 1.5.3.4

• NiceZyme view of 1.5.3.4

• EC2PDB: PDB structures for 1.5.3.4

• PRIAM entry for 1.5.3.4

• PUMA2 entry for 1.5.3.4

• IntEnz: Integrated Enzyme entry for 1.5.3.4

• MetaCyc entry for 1.5.3.4

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050134: N6-methyl-lysine oxidase

• AMIGO entry for GO code 0050134: N6-methyl-lysine oxidase