N-succinylarginine dihydrolase

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In enzymology, a N-succinylarginine dihydrolase (EC 3.5.3.23) is an enzyme that catalyzes the chemical reaction

N₂-succinyl-L-arginine + 2 H₂O $\rightleftharpoons$ N₂-succinyl-L-ornithine + 2 NH₃ + CO₂

Thus, the two substrates of this enzyme are N2-succinyl-L-arginine and H₂O, whereas its 3 products are N2-succinyl-L-ornithine, NH₃, and CO₂.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is N2-succinyl-L-arginine iminohydrolase (decarboxylating). Other names in common use include N2-succinylarginine dihydrolase, arginine succinylhydrolase, SADH, AruB, AstB, and 2-N-succinyl-L-arginine iminohydrolase (decarboxylating). This enzyme participates in arginine and proline metabolism.

[edit] References

IUBMB entry for 3.5.3.23
BRENDA references for 3.5.3.23 (Recommended.)
PubMed references for 3.5.3.23
PubMed Central references for 3.5.3.23
Google Scholar references for 3.5.3.23
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