N-substituted formamide deformylase

From Wikipedia, the free encyclopedia

In enzymology, a N-substituted formamide deformylase (EC 3.5.1.91) is an enzyme that catalyzes the chemical reaction

N-benzylformamide + H₂O formate + benzylamine

Thus, the two substrates of this enzyme are N-benzylformamide and H₂O, whereas its two products are formate and benzylamine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-benzylformamide amidohydrolase. This enzyme is also called NfdA.

[edit] References

• IUBMB entry for 3.5.1.91
• BRENDA references for 3.5.1.91 (Recommended.)
• PubMed references for 3.5.1.91
• PubMed Central references for 3.5.1.91
• Google Scholar references for 3.5.1.91
• Fukatsu H, Hashimoto Y, Goda M, Higashibata H, Kobayashi M (2004). "Amine-synthesizing enzyme N-substituted formamide deformylase: screening, purification, characterization, and gene cloning". Proc. Natl. Acad. Sci. U. S. A. 101: 13726–31. doi:10.1073/pnas.0405082101. PMID 15358859. 

[edit] External links

• IUBMB entry for 3.5.1.91

• KEGG entry for 3.5.1.91

• BRENDA entry for 3.5.1.91

• NiceZyme view of 3.5.1.91

• EC2PDB: PDB structures for 3.5.1.91

• PRIAM entry for 3.5.1.91

• PUMA2 entry for 3.5.1.91

• IntEnz: Integrated Enzyme entry for 3.5.1.91

• MetaCyc entry for 3.5.1.91

• Atomic-resolution structures of enzymes belonging to this class