N-carbamoyl-L-amino-acid hydrolase

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In enzymology, a N-carbamoyl-L-amino-acid hydrolase (EC 3.5.1.87) is an enzyme that catalyzes the chemical reaction

N-carbamoyl-L-2-amino acid (a 2-ureido carboxylate) + H₂O L-2-amino acid + NH₃ + CO₂

Thus, the two substrates of this enzyme are N-carbamoyl-L-2-amino acid and H₂O, whereas its 3 products are L-2-amino acid, NH₃, and CO₂.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-carbamoyl-L-amino acid amidohydrolase.

[edit] References

• IUBMB entry for 3.5.1.87
• BRENDA references for 3.5.1.87 (Recommended.)
• PubMed references for 3.5.1.87
• PubMed Central references for 3.5.1.87
• Google Scholar references for 3.5.1.87
• Ogawa J, Miyake H, Shimizu S (1995). "Purification and characterization of N-carbamoyl-L-amino acid amidohydrolase with broad substrate specificity from Alcaligenes xylosoxidans". Appl. Microbiol. Biotechnol. 43: 1039–43. PMID 8590654. 

[edit] External links

• IUBMB entry for 3.5.1.87

• KEGG entry for 3.5.1.87

• BRENDA entry for 3.5.1.87

• NiceZyme view of 3.5.1.87

• EC2PDB: PDB structures for 3.5.1.87

• PRIAM entry for 3.5.1.87

• PUMA2 entry for 3.5.1.87

• IntEnz: Integrated Enzyme entry for 3.5.1.87

• MetaCyc entry for 3.5.1.87

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050538: N-carbamoyl-L-amino-acid hydrolase

• AMIGO entry for GO code 0050538: N-carbamoyl-L-amino-acid hydrolase